Paediatric IOS and BMI Data for SCD and Asthma
Public Health & Epidemiology
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Provides a detailed longitudinal view of respiratory function in paediatric patients with sickle cell disease and asthma. By recording impulse oscillometry (IOS) measures alongside biometric data like BMI, height, and weight, the study aims to assess how body mass influences airway resistance and reactance. The data accounts for potential confounding factors, including specific pharmacological treatments (hydroxyurea, ICS, LABA) and demographic details. It serves as a vital resource for understanding the intersection of haematological or respiratory conditions and obesity on lung mechanics in vulnerable paediatric populations.
Columns
- Group: Indicates the study cohort: children with sickle cell disease (C-SCD) or African-American children with asthma (C-Asthma).
- Subject ID: A unique identifier assigned to each participant to differentiate individuals.
- Observation number: The sequential number of the measurement for a specific subject, reflecting the longitudinal nature of the study.
- Hydroxyurea: Boolean value indicating if the subject with sickle cell disease received hydroxyurea treatment.
- Asthma: Boolean value indicating if the subject has a diagnosis of asthma.
- ICS: Indicates whether the subject is using inhaled corticosteroids.
- LABA: Indicates whether the subject is using a long-acting beta-agonist.
- Gender: Specifies the gender of the subject (Male or Female).
- Age: The age of the subject in months at the time of observation.
- Height: The subject's height, measured in centimetres.
- Weight (Kg): The subject's weight, measured in kilograms.
- BMI: Calculated Body Mass Index (weight in kg divided by height in metres squared).
- R5Hz_PP: Estimate of airway resistance at 5 Hz obtained via impulse oscillometry.
- R20Hz_PP: Estimate of airway resistance at 20 Hz obtained via impulse oscillometry.
- X5Hz_PP: Estimate of airway reactance at 5 Hz (measure of elasticity/stiffness) via IOS.
- Fres_PP: Estimate of resonant frequency (where reactance transitions from positive to negative) via IOS.
Distribution
- Format: CSV
- Size: 219 valid observations across 16 columns.
- Demographics: The dataset comprises approximately 74% subjects with Sickle Cell Disease (C-SCD) and 26% with Asthma (C-Asthma).
- Gender Balance: Approximately 44% Male, 40% Female, with remaining entries categorised as Other/Unspecified.
- Statistical Range: Age ranges from 50 to 239 months; BMI ranges from approximately 13.7 to 48.1.
Usage
- Paediatric Pulmonology Research: Investigating the correlation between BMI and lung function parameters (resistance and reactance) in children.
- Comparative Disease Analysis: Comparing respiratory mechanics between children with sickle cell disease and those with asthma.
- Pharmacological Impact Studies: Assessing the influence of treatments like hydroxyurea, ICS, and LABA on IOS measures.
- Longitudinal Health Tracking: Modelling changes in respiratory function over time within specific patient cohorts.
Coverage
- Time Range: The study encompasses data collected from 2015 to 2020.
- Demographic Scope: Children with sickle cell disease and African-American children with asthma.
- Geographic Note: While specific location data is not detailed, the demographic profile implies a specific study setting relevant to these populations.
License
CC BY-SA 4.0
Who Can Use It
- Medical Researchers and Biostatisticians
- Paediatricians and Pulmonologists
- Public Health Analysts
- Data Scientists specialising in Healthcare Informatics
Dataset Name Suggestions
- Paediatric IOS and BMI Data for SCD and Asthma
- Sickle Cell and Asthma Respiratory Mechanics Dataset
- Longitudinal Airway Resistance and Reactance Data (2015-2020)
- BMI Impact on Respiratory Function in Children
Attributes
Original Data Source: Paediatric IOS and BMI Data for SCD and Asthma
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