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Memory Priming & Drug Response Dataset
Mental Health & Wellness
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About
This dataset captures an experiment investigating the effects of anti-anxiety medicine on memory recall, specifically when participants are primed with either happy or sad memories. The study was conducted on "novel Islanders" designed to mimic human responses to external factors. The core aim is to understand the obstructive effects of Benzodiazepines (a class of anti-anxiety medication) on long-term potentiation of synapses, metacognition, and memory recall ability. The research acknowledges that positive memories are associated with greater striatum representation, while sad memories may lead to better recall for evolutionary reasons, contrasting with happy memories which might be more prone to false recall. Participants were tested daily for one week to simulate the development of addiction, with memory priming occurring 10 minutes before testing. All participants were over 25 years old to ensure a fully developed pre-frontal cortex, a brain region crucial for higher-level cognition and memory.
Columns
- first_name: The first name of the Islander participant.
- last_name: The last name of the Islander participant.
- age: The age of the Islander participant, ranging from 24 to 83 years, with a mean of 39.5.
- Happy_Sad_group: Indicates whether the participant was primed with Happy ('H') or Sad ('S') memories, with an equal distribution of 50% for each group.
- Dosage: Represents the level of drug dosage administered, categorised as 1 (low), 2 (medium), or 3 (over recommended daily intake). Dosages were administered in a 1:1 ratio for validity.
- Drug: The type of drug administered to the Islander. This includes 'A' for Alprazolam (Xanax, a long-term medication, 1mg/3mg/5mg dosages), 'T' for Triazolam (Halcion, a short-term medication, 0.25mg/0.5mg/0.75mg dosages), and 'S' for Sugar Tablet (Placebo, 1/2/3 tablets).
- Mem_Score_Before: The time in seconds it took for a participant to complete a memory test before any drug exposure. The scores ranged from 27.2 to 110 seconds, with a mean of 58 seconds.
- Mem_Score_After: The time in seconds it took for a participant to complete a memory test after the addiction phase was achieved. Scores ranged from 27.1 to 120 seconds, with a mean of 60.9 seconds.
- Diff: The difference in time, in seconds, between the memory score before and after drug exposure (
Mem_Score_After-Mem_Score_Before). Differences ranged from -40.4 seconds to 49 seconds, with a mean difference of 2.95 seconds.
Distribution
The dataset is provided in a CSV file format, with a file size of 7.61 KB. It contains 9 distinct columns. All columns have 198 valid records, with no mismatched or missing values.
Usage
This dataset is ideal for various research and analytical applications, including:
- Investigating the impact of anti-anxiety medication on cognitive function and memory recall.
- Exploring age-related differences in the effectiveness and side effects of anti-anxiety drugs.
- Analysing the concept of dosage plateauing in anti-anxiety medicine effectiveness.
- Studying the efficacy of placebos within a controlled test environment.
- Examining the influence of emotional memory priming (happy versus sad) on recall ability.
- Researching the long-term adverse effects of benzodiazepines on neurological processes like long-term potentiation and metacognition.
Coverage
The study's participants were novel Islanders designed to simulate real-life human responses. The experiment involved testing participants daily for one week. The demographic scope includes individuals of all genders above 25 years old, ensuring a mature pre-frontal cortex, with participant ages ranging from 24 to 83 years.
License
CC BY-SA 4.0
Who Can Use It
This dataset is particularly relevant for:
- Mental health researchers and psychologists studying anxiety disorders and their treatment.
- Pharmacology experts and pharmaceutical researchers interested in drug efficacy, side effects, and long-term impacts.
- Neuroscience academics exploring memory formation, recall mechanisms, and drug interactions within the brain.
- Data scientists and analysts seeking to model and understand complex medical and behavioural data.
- Students and educators in health sciences, psychology, and statistics looking for real-world experimental data.
Dataset Name Suggestions
- Anti-Anxiety Medication & Memory Recall Study
- Islander Cognitive Drug Effects Data
- Benzodiazepine Memory Experiment
- Memory Priming & Drug Response Dataset
- Cognition and Anxiety Medication Research
Attributes
Original Data Source: Memory Priming & Drug Response Dataset
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